EndoSure Test
EndoSure is a simple, non-invasive test that can help diagnose endometriosis in 30 minutes, from the comfort of our office. The EndoSure Test is a revolutionary diagnostic decision tool that uses proven technology to detect endometriosis at any stage of severity – with nearly 99% accuracy – and results available almost immediately. Veritas Fertility and Surgery is one of only a handful of advanced centers currently offering the EndoSure Test.
While endometriosis may often be suspected based on a woman’s history, symptoms, or diagnostic imaging such as ultrasound or MRI, a definitive diagnosis can only be made with laparoscopy. However, the EndoSure Test can provide an earlier indication that that endometriosis is present, prior to deciding on next steps or proceeding with surgery.
The EndoSure Test can provide critical information to help guide treatment decisions and allows for earlier detection of endometriosis. Early detection allows for earlier treatment. Rapid and accurate testing like this provides women the opportunity to make an informed decision regarding their treatment, including the ability to pursue definitive treatment with laparoscopic excision surgery, instead of suffering with pain or infertility for years without knowing the cause.

How does the EndoSure Test detect endometriosis?
As a chronic inflammatory condition, endometriosis tissue secretes hormone-like substances, called prostaglandins, which lead to inflammation and pain. Organs such as the uterus and bowel are prone to being affected by these prostaglandins which circulate throughout the circulatory system. The most prominent prostaglandins released (PGE2 and PGF-alpha) cause a very specific pattern of contractile activity within the small bowel. These unique contractions of the small bowel can be detected by the EndoSure System through three electrical leads placed on the skin (very similar to an electrocardiogram, or ECG). The EndoSure Test can detect the unique “digital fingerprint” of small bowel myoelectric activity characteristically seen only in women with endometriosis.
What happens during the EndoSure Test?
- Three electrodes are placed on your abdomen; these will remain in place for the duration of the study.
- You will be asked a few questions regarding any pain symptoms you may have.
- You will rest in a recliner for 10-15 minutes as the monitor assesses the baseline myoelectric activity of the small bowel.
- Next, you will drink room temperature water for up to 5 minutes, until you feel full.
- You will relax in the recliner as the EndoSure device records the myoelectric activity of the small bowel for 30 minutes. You’re welcome to doze off during the test if you wish!
- At the end of the test, the leads will be removed. You will receive the results within 1-2 business days of completing the test, after your doctor has assessed your test results.

How should I prepare for the EndoSure Test?
Preparing for the EndoSure Test is very simple.
The EndoSure test should be completed when you are not on your menstrual cycle (we perform the EndoSure Test between cycle days 8-20).
Opioid-containing medications should not be used within the week prior to the EndoSure Test (medications such as Percocet, Vicodin, oxycodone, hydrocodone, and Tylenol #3).
Antispasmotic medications should not be taken within three days prior to the EndoSure Test (medications such as Bentyl, Buscopan, or Levsin).
You should be fasting for 8 hours prior to the test, taking only small sips of water up to 2 hours before the test, if desired.
Nothing should be taken by mouth in the 2 hours prior to the test.
Comfortable, loose-fitting clothing should be worn for the EndoSure Test.
During the test, clothing may need to be adjusted lower down on your hips or above your lower ribs.
You will need to empty your bladder just before starting the test since you will not be able to move from the recliner once the test begins.
The test is safe to complete during ovulation or even if you happen to be pregnant at the time of the test.
Frequently Asked Questions

