EndoSure Test

EndoSure is a simple, non-invasive test that can help diagnose endometriosis in 30 minutes, from the comfort of our office. The EndoSure Test is a revolutionary diagnostic decision tool that uses proven technology to detect endometriosis at any stage of severity – with nearly 99% accuracy – and results available almost immediately. Veritas Fertility and Surgery is one of only a handful of advanced centers currently offering the EndoSure Test.

While endometriosis may often be suspected based on a woman’s history, symptoms, or diagnostic imaging such as ultrasound or MRI, a definitive diagnosis can only be made with laparoscopy. However, the EndoSure Test can provide an earlier indication that that endometriosis is present, prior to deciding on next steps or proceeding with surgery.

The EndoSure Test can provide critical information to help guide treatment decisions and allows for earlier detection of endometriosis. Early detection allows for earlier treatment. Rapid and accurate testing like this provides women the opportunity to make an informed decision regarding their treatment, including the ability to pursue definitive treatment with laparoscopic excision surgery, instead of suffering with pain or infertility for years without knowing the cause.

How does the EndoSure Test detect endometriosis?

As a chronic inflammatory condition, endometriosis tissue secretes hormone-like substances, called prostaglandins, which lead to inflammation and pain. Organs such as the uterus and bowel are prone to being affected by these prostaglandins which circulate throughout the circulatory system. The most prominent prostaglandins released (PGE2 and PGF-alpha) cause a very specific pattern of contractile activity within the small bowel. These unique contractions of the small bowel can be detected by the EndoSure System through three electrical leads placed on the skin (very similar to an electrocardiogram, or ECG). The EndoSure Test can detect the unique “digital fingerprint” of small bowel myoelectric activity characteristically seen only in women with endometriosis.

What happens during the EndoSure Test?

  1. Three electrodes are placed on your abdomen; these will remain in place for the duration of the study.
  2. You will be asked a few questions regarding any pain symptoms you may have.
  3. You will rest in a recliner for 10-15 minutes as the monitor assesses the baseline myoelectric activity of the small bowel.
  4. Next, you will drink room temperature water for up to 5 minutes, until you feel full.
  5. You will relax in the recliner as the EndoSure device records the myoelectric activity of the small bowel for 30 minutes. You’re welcome to doze off during the test if you wish!
  6. At the end of the test, the leads will be removed. You will receive the results within 1-2 business days of completing the test, after your doctor has assessed your test results.

How should I prepare for the EndoSure Test?

Preparing for the EndoSure Test is very simple.

The EndoSure test should be completed when you are not on your menstrual cycle (we perform the EndoSure Test between cycle days 8-20).

Opioid-containing medications should not be used within the week prior to the EndoSure Test (medications such as Percocet, Vicodin, oxycodone, hydrocodone, and Tylenol #3).

Antispasmotic medications should not be taken within three days prior to the EndoSure Test (medications such as Bentyl, Buscopan, or Levsin).

You should be fasting for 8 hours prior to the test, taking only small sips of water up to 2 hours before the test, if desired.

Nothing should be taken by mouth in the 2 hours prior to the test.

Comfortable, loose-fitting clothing should be worn for the EndoSure Test.

During the test, clothing may need to be adjusted lower down on your hips or above your lower ribs.

You will need to empty your bladder just before starting the test since you will not be able to move from the recliner once the test begins.

The test is safe to complete during ovulation or even if you happen to be pregnant at the time of the test.

Frequently Asked Questions

The fee for the EndoSure Test is $600, paid in full at the time of the test.

A portion of this fee may be covered by your insurance, but everyone’s insurance coverage is different. To be safe, it is best to assume insurance will not cover the cost of the test.

No. Since it is important to remain still, undistracted, and quiet during the test to obtain accurate results, family and friends are not allowed in the testing room.

No. To obtain accurate results, patients must not speak or use devices during the EndoSure Test. You will be asked to rest undisturbed in the recliner during the study.

In the rare case that a patient is unable to complete the study for some reason or another, a $500 refund will be given.

No, the results of the test – whether positive or negative – provide useful information to patients and neither a positive nor a negative test result would lead to a refund.

Depending on the severity of the allergy, most patients with an adhesive allergy will be able to complete the test without difficulty. If you have a severe allergy that results in anaphylaxis like reaction, you may not be able to have the test. Your doctor may give you medication to take before the test. Otherwise, if you develop a mild skin reaction after the test you may be directed to take Benadryl or other topical medications.

You must either be an established patient of our practice, or you must have a referral from your doctor to complete the EndoSure Test. Click here to download our EndoSure referral form and have your doctor’s office fax the completed form to our office prior to calling to schedule the test. The results of your EndoSure Test will be sent directly to your doctor’s office, and they will inform you of the results. If you wish to discuss your results in more detail or to discuss treatment options, you may always schedule a consultation with one of our doctors.

No. Having other gastrointestinal issues, such as IBS, Crohn’s disease, or ulcerative colitis, does not affect the accuracy of the EndoSure Test, since the technology behind the test can isolate out only those specific myoelectric patterns seen in women with endometriosis and differentiate those signals from what would be seen with other bowel disorders.

Yes. While the technology behind the EndoSure Test is designed to assess abnormal small bowel activity, the signature pattern of myoelectric signals from the bowel is seen in ALL women with endometriosis, even if they don’t have the bowel symptoms that are often associated with the disease.

Yes. While it is true that some women with endometriosis have no symptoms associated with the disease (so called “silent endometriosis”), the EndoSure Test will be able to accurately detect the presence of endometriosis in such women since the same prostaglandins are still present in asymptomatic endometriosis.


“Dr. Puthoff is amazing! He is compassionate, patient, and very intelligent. He seems to really care, and it feels like you’re in good hands. It is reassuring that he is so good at what he does and still allows you to make your own choices.”

“Dr. Yeung is one of the few doctors who truly listens and does not simply dismiss symptoms. When I go to see him, I know I will be taken seriously and treated with the utmost respect.”

“I am very blessed that the Lord brought Dr. Puthoff and his team into my life. His work and the treatment I received made it possible for us to have another child. That is a priceless joy and we couldn’t say thank you enough to Dr. Puthoff.”

“I would recommend Dr. Yeung to anyone who believes they have endometriosis. For years I was told I couldn’t possibly have endometriosis because I was too young. Dr. Yeung took the time to listen to my story and even prayed with me before surgery.”

“The friendly and welcoming attitude of Dr. Puthoff put me right at ease. He thoroughly explained the procedure and answered all of my questions. I felt extremely confident that he is the right surgeon for my procedure.”

“Dr. Yeung listens and understands you. He makes things easy to understand and supports your decision in your choice for care.”

“My husband and I were very pleased with how approachable and comforting Dr. Puthoff was. He took time to listen and to care. We never felt rushed. He gave us hope. That’s what we needed. Thank you Dr. Puthoff for what you do. Your job truly has a lasting impression and gift on your patients.”

“Because of my first visit and the attentive phone calls I have received since, I am confident I am in caring hands for my upcoming surgery. I feel extremely grateful to be getting such amazing care.”

“Dr. Yeung is incredibly knowledgeable and been such a tremendous help in my journey with endometriosis and infertility. Since surgery, my pain has decreased so much, and we are now taking the next steps to try to get pregnant naturally. I’m forever grateful for Dr. Yeung.”

“I always feel involved in my care. Dr. Puthoff has an excellent bedside manner and demonstrates a high level of professionalism.”

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